Because the coronavirus pandemic spreads throughout states in Nigeria, Osun, Ondo and Ekiti States appear to have discovered reprieve of their medical battle in opposition to the scourge.
PREMIUM TIMES checks revealed that their respective isolation/therapy centres have began utilizing a cocktail comprising chloroquine, hydroxychloroquine and azithromycin medicine as efficient therapy for contaminated sufferers.
Authorities officers who spoke completely and individually with PREMIUM TIMES, admitted that though no drug had been authorised for the therapy of the illness, chloroquine notably has change into a viable different with encouraging outcomes to this point.
Nigeria is grappling with the group unfold of the illness which is progressively turning into intractable, with a fast rise within the variety of instances each day.
Lagos is the epicentre of the illness. Nonetheless, elevated instances and deaths in Kano have change into one other supply of concern within the combat in opposition to the illness.
As of 11.25 p.m. on April 22, the nation had a complete of 873 instances, with 197 sufferers discharged. About 28 deaths have been recorded to this point.
Of the quantity, Lagos had 504; FCT, 119; Kano, 73; Ogun, 24. Osun has 20 instances, Ondo, three and Ekiti, 4.
In Osun, 19 of the confirmed instances have been handled and discharged. Just one remains to be held again on the therapy centre awaiting when he can be confirmed damaging.
The state turned affected in March when a number of individuals returned from Ivory Coast; 27 of them, and have been instantly remoted and examined for the virus.
Those that examined constructive have been confined on the Ejigbo COVID-19 Isolation and Remedy Centre the place they have been supplied with therapy.
The Osun State Commissioner for Well being, Rafiu Isamatu, informed PREMIUM TIMES though there’s a lack of a breakthrough within the therapy of the illness worldwide, the efficacy of some already identified medicine has aided the medical containment of the virus within the state.
“You have got mentioned all of it, that there isn’t any identified drug for COVID-19,” he mentioned. “Principally everyone is simply doing trial and error.”
He added an important factor guiding the administering of care by the state’s medical crew was to make sure that no matter remedy was given to sufferers, is not going to be injurious to them and ought to be seen as working.
“I suppose within the U.S. they’re utilizing hydroxychloroquine and azithromycin and I feel few journals have truly supported it although there isn’t any identified empirical proof that may very well be adopted because the therapy for COVID-19,” Mr Isamatu mentioned.
“Anecdotal proof exhibits that it really works. There’s this American Journal of Drugs which equally provides credence to the usage of hydroxylchloroquine. Nonetheless, it has not been formally recognised as the most effective therapy for COVID-19.
“What we did in Osun…keep in mind we had 20 instances and so they have been discharged, we solely have one affected person left. No matter we did to our affected person should have labored and we did our greatest to make sure that we didn’t give any drug that has not been identified to deal with one ailment or the opposite.
“So, those that had no signs, we gave them immune boosters, excessive dose of vitamin C, Zinc Selenium; and we handled them symptomatically. If anyone develops any temperature or some other factor, we handled them, that’s what we, docs name symptomatic therapy.
“Now, those that have been sicker than the remaining, these are those we handled with hydroxylchloroquine and Azithromycin. Azithromycin is a macrolide within the class of erythromycin and related medicine.”
The commissioner defined that hitherto, hydroxychloroquine was used to deal with gout, which is the buildup of protein within the joints, including that it has now been discovered to be efficient within the administration of coronavirus.
“For those who didn’t have any identified allergy to chloroquine, all of them did properly,” he mentioned. “We had no antagonistic results to hydroxychloroquine. That was what we did for our sufferers in Osun.”
Mr Isamatu revealed that the one affected person left on the therapy centre has not developed any signs in any respect, however shortly added that his may very well be deadlier, since he might simply unfold the virus if allowed to enter the communities with it.
Mr Isamatu mentioned there have been totally different strains of COVID-19, noting that “those that we now have in Africa, notably in Nigeria, appears to be a milder one”.
“These individuals we now have misplaced, 99.9 per cent of them had one underlying pathology or the opposite,” he mentioned. “There’s nothing to stigmatise anyone about COVID-19. Some are refusing to come back up for check due to that.”
Ekiti State recorded its first demise on account of the virus within the case of a 29-year-old well being employee who was additionally pregnant. She had a caesarean part and had a coronary heart assault, regardless that she examined constructive for the virus.
The state had its index case on March 13 in a 37-year-old man who examined constructive for coronavirus after he got here in touch with an American vacationer.
After weeks of therapy and monitoring on the isolation centre, the person examined damaging for coronavirus.
Ekiti Commissioner for Well being, Mojisola Yahaya-Kolade, in a phone interview mentioned the sufferers have been being handled with chloroquine.
“Any medical physician will undergo the investigational medicine which have been utilized in different international locations of the world that had COVID-19 earlier than us, and there are such a lot of write-ups and methods individuals have put forth on the correct technique to deal with them,” she mentioned.
“We deal with them symptomatically, in case you have excessive temperature, we give them one thing to decrease the temperature, if any person is having pains, we deal with the ache. No matter that’s wanted, you give it to them.
“Extra importantly in Ekiti State, we’re utilizing chloroquine as it’s being utilized in different international locations of the world, and we’re supporting chloroquine with what is known as azithromycin and that’s what we’re doing. We are also giving supportive care.
“To the most effective of our skill, all different sufferers we now have handled, they’re bettering and getting higher. Aside from the girl that had caesarean part and had cardiac arrest,” she added.
“How do we all know that they’re getting higher? We are literally testing the tradition once more and it turns damaging and the second constructive turns damaging, meaning the individual is healed, and we feature out the check at the least two instances.”
In Ondo, the Commissioner for Well being, Wahab Adegbenro, confirmed that chloroquine was the drug administered to the sufferers on the state therapy centre.
The index case of the illness was a navy officer who arrived with signs of the virus after a world engagement in India. He was remoted, however the physician who attended to him on the Military medical centre was later contaminated.
A 3rd case additionally occurred after an airport employee travelled with the virus from Lagos to Ijoka, in Akure and was promptly picked up for a check. He examined constructive.
The index case has since been discharged after officers mentioned he had examined damaging twice for the virus after weeks of therapy.
“As you’ve got mentioned, there isn’t any particular therapy now, however we’re nonetheless counting on symptomatic therapy and we additionally use hydroxychloroquine and arythromycin,” Mr Adegbenro mentioned, when requested how he had been treating the sufferers.
He mentioned docs additionally deal with the sufferers ‘symptomatically’. He famous that the chloroquine therapy had been efficient.
“It’s efficient, as a result of even the second case now has examined damaging,” he mentioned. “It’s doubtless he goes dwelling this weekend.
“We’re solely ready for the second check going by the rules by NCDC, the affected person has to check damaging twice earlier than we are able to discharge him.
“We hope that by this weekend or on Monday, if the outcomes come again, we are going to most likely discharge him.
“The third case can be not doing badly. He’s recovering, there isn’t any trigger for alarm. All of them will go dwelling as a result of the instances have been picked up early. Whenever you decide them early, the restoration is quicker. The comply with up contacts that we did assessments on, all of them returned damaging.”
Chloroquine, which was broadly used up to now to deal with malaria sufferers in Nigeria, was later banned by the authorities.
In March, there have been stories of chloroquine poisoning after three individuals have been hospitalised in Lagos for chloroquine overdose of their alleged makes an attempt to stop an infection.
The Lagos authorities later issued a press release warning individuals in opposition to self-medication.
This improvement got here after the USA President, Donald Trump, had endorsed the usage of the drug for the therapy of the illness within the wake of an avalanche of confirmed instances and deaths within the nation.
The U.S. Meals and Drug Administration shortly responded saying it was but to approve its use for that goal because it was nonetheless present process scientific assessments for a doable use to deal with COVID-19.
The FDA had solely authorised it for emergency use, solely making use of to sure COVID-19 sufferers, who should meet particular standards to entry the therapy.
The views expressed in this article are the writer’s opinion, they do not reflect the views of the Publisher of NEWS 4 NAIJA. Please report any fake news , misinformation or defamatory statements to [email protected]
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